My primary research interests include analysis of missing data, design, implementation and analysis of clinical trials, and statistical machine learning. Other research interests are longitudinal data analysis, semi-parametric statistics, diagnostic tests without gold standard, modeling with stochastic processes, and analysis of gene expression data. The fields of application include breast cancers, environmental health in petroleum industry workers, reproductive health of women, pancreatitis, critical care medicine and inflammatory bowel disease.
Education
2001 | University of Michigan, Ann Arbor, MI | PhD of Biostatistics
1996 | Johns Hopkins University, Baltimore, MD | MA of Mathematics
1994 | Beijing University, Beijing, China | MS of Mathematics
1991 | Beijing University, Beijing, China | BS of Mathematics
2013 | Chapter Service Award | The Council of Chapters, American Statistical Association
2010 | Best of ASCO Abstract | The American Society of Clinical Oncology Annual Meeting 2010
2001 | Student Paper Award | The Eastern Northern Region of the International Biometric Society
Teaching
Fall, 2021 | Biostat 2065: Analysis of Incomplete Data
Spring, 2022 | Biostat 2061: Likelihood theory and applications
Selected Publications
- Squifflet P, Saad ED, Loibl S, van Mackelenbergh MT, Untch M, Rastogi P, Gianni L, Schneeweiss A, Conte P, Piccart M, Bonnefoi H, Jackisch C, Nekljudova V, Tang G, Valagussa P, Neate C, Gelber R, Poncet C, Heinzmann D, Denkert C, Geyer CE Jr, Cortes J, Guarneri V, de Azambuja E, Cameron D, Ismael G, Wolmark N, Cortazar P, Buyse M. Re-Evaluation of Pathologic Complete Response as a Surrogate for Event-Free and Overall Survival in Human Epidermal Growth Factor Receptor 2-Positive, Early Breast Cancer Treated With Neoadjuvant Therapy Including Anti-Human Epidermal Growth Factor Receptor 2 Therapy. J Clin Oncol. 2023 Jun 1;41(16):2988-2997.
- Fernandez-Martinez A, Rediti M, Tang G, Pascual T, Hoadley KA, Venet D, Rashid NU, Spears PA, Islam MN, El-Abed S, Bliss J, Lambertini M, Di Cosimo S, Huobe J, Goerlitz D, Hu R, Lucas PC, Swain SM, Sotiriou C, Perou CM, Carey LA. Tumor Intrinsic Subtypes and Gene Expression Signatures in Early-Stage ERBB2/HER2-Positive Breast Cancer: A Pooled Analysis of CALGB 40601, NeoALTTO, and NSABP B-41 Trials. JAMA Oncol. 2024 Mar 28.
- Rastogi P, Tang G, Hassan S, Geyer CE Jr, Azar CA, Magrinat GC, Suga JM, Bear HD, Baez-Diaz L, Sarwar S, Boileau JF, Brufsky AM, Shibata HR, Bandos H, Paik S, Yothers G, Swain SM, Mamounas EP, Wolmark N. Long-term outcomes of dual vs single HER2-directed neoadjuvant therapy in NSABP B-41. Breast Cancer Res Treat. 2023 Jun;199(2):243-252
- Tang G, Little RJ, Raghunathan TE. Analysis of Multivariate Missing Data with Nonignorable Nonresponse. Biometrika. 2003; 4 (90):747-764.
- Tang G, Little RJ, Raghunathan TE. Analysis of Multivariate Monotone Missing Data by a Pseudolikelihood Method. In: Lin D, Heagerty PJ, editors. Proceedings of the Second Seattle Symposium in Biostatistics: Analysis of Correlative Data. Lecture Notes in Statistics. New York: Springer-Verlag, 2004.
- Paik S, Shak S, Tang G, Kim C, Baker J, Cronin M, Baehner FL, Walker MG, Watson D, Park T, Hiller W, Fisher ER, Wickerham DL, Bryant J, Wolmark N. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. The New England journal of medicine. 2004 Dec 30; 351 (27):2817-26. PMID: 15591335.
- Paik S, Tang G, Shak S, Kim C, Baker J, Kim W, Cronin M, Baehner FL, Watson D, Bryant J, Costantino JP, Geyer CE Jr, Wickerham DL, Wolmark N. Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2006 Aug 10; 24 (23):3726-34. PMID: 16720680.
- Tang G, Shak S, Paik S, Anderson SJ, Costantino JP, Geyer CE Jr, Mamounas EP, Wickerham DL, Wolmark N. Comparison of the prognostic and predictive utilities of the 21-gene Recurrence Score assay and Adjuvant! for women with node-negative, ER-positive breast cancer: results from NSABP B-14 and NSABP B-20. Breast cancer research and treatment. 2011 May; 127 (1):133-42. PMID: 21221771.
- Haggerty CL, Seifert ME, Tang G, Olsen J, Bass DC, Karumanchi SA, Ness RB. Second trimester anti-angiogenic proteins and preeclampsia. Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health. 2012; 2 (2):158-163. PMCID: PMC3375839. PMID: 22712058.
- Bear HD, Tang G, Rastogi P, Geyer CE Jr, Robidoux A, Atkins JN, Baez-Diaz L, Brufsky AM, Mehta RS, Fehrenbacher L, Young JA, Senecal FM, Gaur R, Margolese RG, Adams PT, Gross HM, Costantino JP, Swain SM, Mamounas EP, Wolmark N. Bevacizumab added to neoadjuvant chemotherapy for breast cancer. The New England journal of medicine. 2012 Jan 26; 366 (4):310-20. PMCID: PMC3401076. PMID: 22276821.
- Schnatter AR, Glass DC, Tang G, Irons RD, Rushton L. Myelodysplastic syndrome and benzene exposure among petroleum workers: an international pooled analysis. Journal of the National Cancer Institute. 2012 Nov 21; 104 (22):1724-37. PMCID: PMC3502195. PMID: 23111193.
- Zhu F, Tang G. An Index of Local Sensitivity to Nonignorability for a Pseudolikelihood Method. Communications in Statistics - Theory and Methods. 2013 Feb; 42 (6):954-973.
- Crager M, Tang G. Patient-specific meta-analysis for risk assessment using multivariate proportional hazards regression. Journal of Applied Statistics. 2014 Dec; 41 (12):2676-2695.
- Abberbock, J., Anderson, S., Rastogi, P., & Tang, G. (2019). Assessment of effect size and power for survival analysis through a binary surrogate endpoint in clinical trials. Statistics in Medicine, 38(3), 301-314. doi:10.1002/sim.7981
- Swain SM, Tang G, Brauer HA, Goerlitz DS, Lucas PC, Robidoux A, Harris BT, Bandos H, Ren Y, Geyer CE, Rastogi P, Mamounas EP, Wolmark N. NSABP B-41, a Randomized Neoadjuvant Trial: Genes and Signatures Associated with Pathologic Complete Response. Clin Cancer Res. 2020 May 5;. doi: 10.1158/1078-0432.CCR-20-0152. [Epub ahead of print] PubMed PMID: 32371537.
- Sparano JA, Crager MR, Tang G, Gray RJ, Stemmer SM, Shak S. Development and Validation of a Tool Integrating the 21-Gene Recurrence Score and Clinical-Pathological Features to Individualize Prognosis and Prediction of Chemotherapy Benefit in Early Breast Cancer. J Clin Oncol. 2021 Feb 20;39(6):557-564.
- Xiaoqing Tan, Judah Abberbock, Priya Rastogi, Gong Tang. Identifying Principal Stratum Causal Effects Conditional on a Post-treatment Intermediate Response Proceedings of the First Conference on Causal Learning and Reasoning, PMLR 177:734-753, 2022.
- Wang XS, Lee S, Zhang H, Tang G, Wang Y. An integral genomic signature approach for tailored cancer therapy using genome-wide sequencing data. Nat Commun. 2022 May 26;13(1):2936. doi: 10.1038/s41467-022-30449-7. PubMed PMID: 35618721.
